When opening a document in Adobe Acrobat Reader DC you may be presented with the following error message:

The Instruction at 0x76e3e1e1 referenced memory at 0x76e3e1e1.  The memory could not be read.  Click on OK to terminate the program.

The-Insruction-Referenced-Adobe-Acrobat-Reader

To resolve this error usually involves one of two solutions.

Solution 1

Step 1

Uninstall Acrobat Reader from the Control Panel

Step 2

Use the Adobe Reader Removal Tool to completely remove any traces of the program

Step 3

Restart the Computer

Step 4

Install Adobe Reader Again

Solution 2

If Solution 1 doesn’t work, disabling Protected view will usually resolve the problem until the root cause can be worked out.

Step 1

Whilst Adobe Acrobat Reader DC is open click on Edit

Step 2

Click on Preferences

Step 3

Click on Security (Enhanced)

Step 4

Turn off protected mode and protected mode when starting up.

Note

If the following methods don’t work there may be other issues with the computer that need resolving.